Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep463 | Pituitary and Neuroendocrinology | ECE2021

Epidemiology of acromegaly in south-eastern Norway

Falch Camilla Maria , Olarescu Cristina , Bollerslev Jens , Dekkers Olaf M. , Heck Ansgar

ObjectiveIn order to improve therapeutic outcomes for patients with acromegaly, new treatment algorithms have been developed over the last decades. Valid epidemiological data of acromegaly in Norway is lacking. The overall aim of this study was to investigate incidence, prevalence and mortality of acromegaly in South-Eastern Norway, and to investigate effects of new treatment algorithms.Design and methodPatie...

ea0049oc8.3 | Neuroendocrinology | ECE2017

RNA sequencing and RT-qPCR identify different gene expression profiles in fast- vs. slow-growing non-functioning pituitary adenomas

Falch Camilla Maria , Sundaram Arvind Y.M. , Oystese Kristin Astrid Berland , Normann Kjersti Ringvoll , Silamikelis Ivars , Andersen Marianne , Bollerslev Jens , Olarescu Nicoleta Cristina

Background: Non-functioning pituitary adenomas (NFPAs) necessitate prolonged clinical, biochemical and radiological observation, constituting a significant burden in terms of medical resources and societal costs. Reliable biomarkers associated with aggressiveness and recurrence of NFPAs are lacking. As the growth of tumor remnants is highly variable, molecular markers that can predict growth potential and tumor behavior are necessary.Aim: To identify tar...